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Identifying genetic variants associated with side effects of antidepressant treatment: A systematic review.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

da Rocha Zurchimitten Gabriel, Camerini Laísa, Izídio Geison Souza, Ghisleni Gabriele

Abstract excerpt

Major Depressive Disorder (MDD) is one of the most prevalent neurobiological disorders globally. Antidepressant medications are the first-line treatment for managing symptoms. However, over time, pharmacotherapy has been linked to several challenges, primarily due to the wide array of side effects that often reduce patient adherence to treatment. The literature suggests that these side effects may be influenced...

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Antidepressive Agents
Genetic Variation
Major Depressive Disorder
Polymorphism, Genetic

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PMID: 39369809
DOI: 10.1016/j.pnpbp.2024.111154

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