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Article

Functional structure of the promoter regions for the predominant low molecular weight isoforms of tropomyosin in human kidney cells.

Journal of cellular biochemistry - 1 Nov 2012

Savill Stuart A, Leitch Helen F, Harvey John N, Thomas Trevor H

Abstract excerpt

High and low molecular weight (LMW) tropomyosin isoforms, by regulation of actin filaments, have a major role in the regulation of cell behaviour. They affect malignant transformation, motility, differentiation, metastasis and cell membrane protein presentation. Expression of LMW isoforms from the TPM1 and TPM3 genes have an important role in these effects but the regulation of their expression is unknown....

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Source

Identifiers

PMID: 22740512
DOI: 10.1002/jcb.24236

Genes

TPM1
TPM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Functional structure of the promoter regions for the predominant low molecular weight isoforms of tropomyosin in human kidney cells.PMID 22740512Read ↗

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