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Article

Construction, expression and unexpected regulatory properties of a tropomyosin mutant with a 31-residue deletion at the C-terminus (exon 9).

European journal of biochemistry - 27 Dec 1990

Bartegi A, Ferraz C, Fattoum A, Sri Widada J, Heitz F, Kassab R, Liautard J P

Abstract excerpt

The cDNA coding for human skeletal muscle beta-tropomyosin was expressed in Escherichia coli to produce an unacetylated beta-tropomyosin. This cDNA was deleted from the sequence corresponding to the exon 9 and expressed in E. coli to produce an unacetylated beta-tropomyosin mutant lacking the C-terminal residues 254-284. The main structural and functional properties of the two isolated proteins, designated...

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Identifiers

PMID: 2148519
DOI: 10.1111/j.1432-1033.1990.tb19478.x

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