Article
Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing.
Molecular and cellular biology - 1 Apr 1990
Lees-Miller J P, Goodwin L O, Helfman D M
Abstract excerpt
cDNA clones encoding three novel tropomyosins, termed TMBr-1, TMBr-2, and TMBr-3, were isolated and characterized from a rat brain cDNA library. All are derived from a single gene, which was previously found to express striated muscle alpha-tropomyosin and a number of other tropomyosin isoforms v...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Cloning, Molecular
- Exons
- Gene Library
- Genes
- Genetic Variation
- Introns
- Molecular Sequence Data
- Plasmids
- Promoter Regions, Genetic
- RNA Splicing
- RNA, Messenger
- Rats
- Restriction Mapping
- Sequence Homology, Nucleic Acid