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Article

Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing.

Molecular and cellular biology - 1 Apr 1990

Lees-Miller J P, Goodwin L O, Helfman D M

Abstract excerpt

cDNA clones encoding three novel tropomyosins, termed TMBr-1, TMBr-2, and TMBr-3, were isolated and characterized from a rat brain cDNA library. All are derived from a single gene, which was previously found to express striated muscle alpha-tropomyosin and a number of other tropomyosin isoforms via an alternative splicing mechanism (N. Ruiz-Opazo and B. Nadal-Ginard, J. Biol. Chem. 262:4755-4765, 1987; D. F....

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Identifiers

PMID: 2320008
DOI: 10.1128/mcb.10.4.1729-1742.1990
PMCID: PMC362279

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