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Article

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4.

Annals of the rheumatic diseases - 1 Jan 2013

Wang Chuan, Sandling Johanna K, Hagberg Niklas, Berggren Olof, Sigurdsson Snaevar, Karlberg Olof, Rönnblom Lars, Eloranta Maija-Leena, Syvänen Ann-Christine

Abstract excerpt

BACKGROUND: The transcription factors interferon regulatory factor 5 (IRF5) and signal transducer and activator of transcription 4 (STAT4) are encoded by two of the strongest susceptibility genes for systemic lupus erythematosus (SLE). OBJECTIVE: To investigate the target genes and functional roles of IRF5 and STAT4 in human peripheral blood mononuclear cells (PBMCs). METHODS: Chromatin...

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Source

Identifiers

PMID: 22730365
DOI: 10.1136/annrheumdis-2012-201364

Genes

STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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