Article
No genetic association between polymorphisms in the kainate-type glutamate receptor gene, GRIK4, and schizophrenia in the Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Apr 2008
Li Zhiqiang, He Zangdong, Tang Wei, Tang Ruqi, Huang Ke, Xu Zhao, Xu Yifeng, Li Lingzhen, Li Xingwang, Feng Guoying, He Lin, Shi Yongyong
Abstract excerpt
BACKGROUND: Schizophrenia is a chronic psychiatric disorder with a strong genetic component. Several studies have suggested that dysfunctions in the glutamatergic transmission are linked to the pathogenesis of schizophrenia, and that the kainate ionotropic glutamate receptors are involved in this mechanism. A recent study provides cytogenetic and genetic evidence to support a role for the kainate-type glutamate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
