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Article

Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia.

Psychiatry research - 15 Dec 2002

Shibata Hiroki, Shibata Atsushi, Ninomiya Hideaki, Tashiro Nobutada, Fukumaki Yasuyuki

Abstract excerpt

The glutamatergic dysfunction hypothesis of schizophrenia suggests genes involved in glutamatergic transmission as candidates for schizophrenia-susceptibility genes. The GluR6 kainate receptor gene GRIK2 is located on chromosome 6q16.3-q21, a schizophrenia susceptibility region, as suggested by multiple linkage studies. We examined 15 SNPs evenly distributed in the entire GRIK2 region (>700 kb) in Japanese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12467946
DOI: 10.1016/s0165-1781(02)00231-7

Genes

GRIK2

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