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Article

Host genetic control of gut microbiome composition.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2021

Bubier Jason A, Chesler Elissa J, Weinstock George M

Abstract excerpt

The gut microbiome plays a significant role in health and disease, and there is mounting evidence indicating that the microbial composition is regulated in part by host genetics. Heritability estimates for microbial abundance in mice and humans range from (0.05-0.45), indicating that 5-45% of inter-individual variation can be explained by genetics. Through twin studies, genetic association studies, systems...

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Identifiers

PMID: 34159422
DOI: 10.1007/s00335-021-09884-2
PMCID: PMC8295090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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