Using the collaborative cross to identify the role of host genetics in defining the murine gut microbiome

doi:10.1186/s40168-023-01552-8

Article

Using the collaborative cross to identify the role of host genetics in defining the murine gut microbiome

7 Jul 2023

Abstract excerpt

BACKGROUND: The human gut microbiota is a complex community comprised of trillions of bacteria and is critical for the digestion and absorption of nutrients. Bacterial communities of the intestinal microbiota influence the development of several conditions and diseases. We studied the effect of host genetics on gut microbial composition using Collaborative Cross (CC) mice. CC mice are a panel of mice that are...

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