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Article

Unravelling the effects of the environment and host genotype on the gut microbiome.

Nature reviews. Microbiology - 1 Apr 2011

Spor Aymé, Koren Omry, Ley Ruth

Abstract excerpt

To what extent do host genetics control the composition of the gut microbiome? Studies comparing the gut microbiota in human twins and across inbred mouse lines have yielded inconsistent answers to this question. However, candidate gene approaches, in which one gene is deleted or added to a model host organism, show that a single host gene can have a tremendous effect on the diversity and population structure of...

Topics

Adaptive Immunity
Animals
Diet
Environment
Gastrointestinal Tract
Genes
Genotype
Humans
Immunity, Innate
Metagenome
Mice
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Consortia

Twins

Source

Identifiers

PMID: 21407244
DOI: 10.1038/nrmicro2540

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