Article
High-resolution association mapping of atherosclerosis loci in mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2012
Bennett Brian J, Orozco Luz, Kostem Emrah, Erbilgin Ayca, Dallinga Marchien, Neuhaus Isaac, Guan Bo, Wang Xuping, Eskin Eleazar, Lusis Aldons J
Abstract excerpt
OBJECTIVE: The purpose of this study was to fine map previously identified quantitative trait loci affecting atherosclerosis in mice using association analysis. METHODS AND RESULTS: We recently showed that high-resolution association analysis using common inbred strains of mice is feasible if corrected for population structure. To use this approach for atherosclerosis, which requires a sensitizing mutation, we...
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