Article
Ontogeny and characterization of factor XIIIa+ cells in developing human skin.
Anatomy and embryology - 1 Jan 1996
Gibran N S, Nickoloff B J, Holbrook K A
Abstract excerpt
Factor XIIIa (FXIIIa), a coagulation transglutaminase, is a cytoplasmic marker for dermal dendritic cells reported to be bone marrow-derived, phagocytic and antigen-presenting. In non-inflamed skin, these cells populate the papillary dermis in a perivascular distribution. They are increased in dermatoproliferative disorders and have been implicated as dermal stimulants for psoriatic hyperkeratosis. Since...
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