Article
A clinical, pathologic, and molecular study of p53 and murine double minute 2 in penile carcinogenesis and its relation to prognosis.
Human pathology - 1 Apr 2012
Rocha Rafael Malagoli, Ignácio Julianna Alves, Jordán José, Carraro Dirce Maria, Lisboa Bianca, Lopes Ademar, Carvalho Kátia Cândido, da Cunha Isabela Werneck, Cubilla Antônio, Guimarães Gustavo Cardoso, Vassallo José, Soares Fernando Augusto
Abstract excerpt
Penile carcinoma constitutes up to 16% of male malignancies in developing countries. Changes in the p53 and murine double minute 2 pathway are important events in various cancers. Associate alterations in murine double minute 2 and p53 expression were evaluated by molecular techniques, with the clinical data of 297 cases of penile carcinoma. Automated immunohistochemistry was performed for murine double minute 2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
