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Article

The identification of transcriptional targets of Ascl1 in oligodendrocyte development.

Glia - 1 Oct 2012

Ueno Takaaki, Ito Junichi, Hoshikawa Shinya, Ohori Yasuo, Fujiwara Sayaka, Yamamoto Shinichi, Ohtsuka Toshiyuki, Kageyama Ryoichiro, Akai Masami, Nakamura Kozo, Ogata Toru

Abstract excerpt

The basic helix-loop-helix (bHLH) transcription factor Ascl1 plays crucial roles in both oligodendrocyte development and neuronal development; however, the molecular target of Ascl1 in oligodendrocyte progenitor cells (OPCs) remains elusive. To identify the downstream targets of Ascl1 in OPCs, we performed gene expression microarray analysis and identified Hes5 as a putative downstream target of Ascl1. In vivo...

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Identifiers

PMID: 22714260
DOI: 10.1002/glia.22369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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