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Article

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.

Developmental cell - 1 Nov 2006

Stolt C Claus, Schlierf Anita, Lommes Petra, Hillgärtner Simone, Werner Torsten, Kosian Thomas, Sock Elisabeth, Kessaris Nicoletta, Richardson William D, Lefebvre Veronique, Wegner Michael

Abstract excerpt

The myelin-forming oligodendrocytes are an excellent model to study transcriptional regulation of specification events, lineage progression, and terminal differentiation in the central nervous system. Here, we show that the group D Sox transcription factors Sox5 and Sox6 jointly and cell-autonomously regulate several stages of oligodendrocyte development in the mouse spinal cord. They repress specification and...

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Identifiers

PMID: 17084361
DOI: 10.1016/j.devcel.2006.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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