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Article

Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon.

Neural development - 10 Feb 2009

Wang Bei, Waclaw Ronald R, Allen Zegary J, Guillemot Francois, Campbell Kenneth

Abstract excerpt

BACKGROUND: The homeobox gene Gsx2 (formerly Gsh2) is known to regulate patterning in the lateral ganglionic eminence (LGE) of the embryonic telencephalon. In its absence, the closely related gene Gsx1 (previously known as Gsh1) can partially compensate in the patterning and differentiation of ventral telencephalic structures, such as the striatum. However, the cellular and molecular mechanisms underlying this...

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Identifiers

PMID: 19208224
DOI: 10.1186/1749-8104-4-5
PMCID: PMC2644683

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