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Single nucleotide polymorphisms in the mitochondrial displacement loop region modifies malignant melanoma: a study in Chinese Han population.

Mitochondrial DNA - 1 Apr 2015

Zhang Wenjin, Wang Wei, Jia Zhifeng

Abstract excerpt

Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) may be associated with an increased cancer risk. We investigated the malignant melanoma (MM) risk profile of D-loop SNPs in a case-controlled study in Chinese Han population. A statistically significant increase in SNP frequency for the T16362C, A16399G and T195C alleles was observed in MM...

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Identifiers

PMID: 24660917
DOI: 10.3109/19401736.2014.900613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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