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Article

A novel EML4-ALK variant: exon 6 of EML4 fused to exon 19 of ALK.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2012

Penzel Roland, Schirmacher Peter, Warth Arne

Abstract excerpt

INTRODUCTION: Cytotoxic chemotherapy remains the mainstay of treatment for most patients with advanced disease. Recently, anaplastic lymphoma kinase (ALK) expression as a major target for successful treatment with ALK inhibitors was detected in a subset of non-small-cell lung carcinomas, usually...

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Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung
Share to Gene Rearrangement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoenzyme Techniques

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Share to Oncogene Proteins, Fusion

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Source

Identifiers

PMID: 22706607
DOI: 10.1097/JTO.0b013e3182598af3

Genes

ALK
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22706607-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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