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Article

Molecular breakdown: a comprehensive view of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer.

The Journal of pathology - 1 Nov 2017

Noh Ka-Won, Lee Mi-Sook, Lee Seung Eun, Song Ji-Young, Shin Hyun-Tae, Kim Yu Jin, Oh Doo Yi, Jung Kyungsoo, Sung Minjung, Kim Mingi, An Sungbin, Han Joungho, Shim Young Mog, Zo Jae Ill, Kim Jhingook, Park Woong-Yang, Lee Se-Hoon, Choi Yoon-La

Abstract excerpt

Most anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancers (NSCLCs) show good clinical response to ALK inhibitors. However, some ALK-rearranged NSCLC patients show various primary responses with unknown reasons. Previous studies focused on the clinical aspects of ALK fusions in small cohorts, or were conducted in vitro and/or in vivo to investigate the function of ALK. One of the suggested...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

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Share to Microtubule-Associated Proteins

Share to Oncogene Proteins, Fusion

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Source

Identifiers

PMID: 28741662
DOI: 10.1002/path.4950

Genes

ALK
EML4
GCC2
LMO7
PHACTR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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