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Article

The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS.

Cancer - 15 Apr 2009

Wong Daisy Wing-Sze, Leung Elaine Lai-Han, So Kimpton Kam-Ting, Tam Issan Yee-San, Sihoe Alan Dart-Loon, Cheng Lik-Cheung, Ho Kwok-Keung, Au Joseph Siu-Kie, Chung Lap-Ping, Pik Wong Maria

Abstract excerpt

BACKGROUND: The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic profiles of EML4-ALK in Chinese patients with NSCLC. METHODS: EML4-ALK was investigated in 266...

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Source

Identifiers

PMID: 19170230
DOI: 10.1002/cncr.24181

Genes

ALK
EML4
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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