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Article

A case of lung adenocarcinoma harboring EGFR mutation and EML4-ALK fusion gene.

BMC cancer - 26 Nov 2012

Tanaka Hisashi, Hayashi Akihito, Morimoto Takeshi, Taima Kageaki, Tanaka Yoshihito, Shimada Michiko, Kurose Akira, Takanashi Shingo, Okumura Ken

Abstract excerpt

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Epidermal growth factor receptor (EGFR)--tyrosine kinase inhibitor (TKI) is used for the patients with EGFR-mutant lung cancer. Recently, phase III studies in the patients with EGFR-mutant demonstrated that EGFR-TKI monotherapy improved progression-free survival compared with platinum-doublet chemotherapy. The echinoderm...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oncogene Proteins, Fusion

Source

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Identifiers

PMID: 23181703
DOI: 10.1186/1471-2407-12-558
PMCID: PMC3515412

Genes

EGFR
ALK
EML4
KRAS

Provenance

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