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Article

Clinicopathologic features of non-small-cell lung cancer with EML4-ALK fusion gene.

Annals of surgical oncology - 1 Mar 2010

Takahashi Tsuyoshi, Sonobe Makoto, Kobayashi Masashi, Yoshizawa Akihiko, Menju Toshi, Nakayama Ei, Mino Nobuya, Iwakiri Shotaro, Sato Kiyoshi, Miyahara Ryo, Okubo Kenichi, Manabe Toshiaki, Date Hiroshi

Abstract excerpt

BACKGROUND: A fusion gene between echinoderm microtubule-associated protein-like 4 (EML4) and the anaplastic lymphoma kinase (ALK) has recently been identified in nonsmall-cell lung cancers (NSCLCs). We screened for EML4-ALK fusion genes and examined the clinicopathological and genetic characteristics of fusion-harboring NSCLC tumors. METHODS: We examined 313 NSCLC samples from patients who underwent resection at...

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Source

Identifiers

PMID: 20183914
DOI: 10.1245/s10434-009-0808-7

Genes

ALK
EML4
EGFR
ERBB2
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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