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DNA methylation biomarkers of intellectual/developmental disability across the lifespan

19 Feb 2025

Abstract excerpt

Epigenetic mechanisms, including DNA methylation, act at the interface of genes and environment by allowing a static genome to respond and adapt to a dynamic environment during the lifespan of an individual. Genome-wide DNA methylation analyses on a wide range of human biospecimens are beginning to identify epigenetic biomarkers that can predict risk of intellectual/developmental disabilities (IDD). DNA...

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PMID: 39972408
DOI: 10.1186/s11689-025-09598-5

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