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Article

DNA methylation and brain structure and function across the life course: A systematic review.

Neuroscience and biobehavioral reviews - 1 Jun 2020

Wheater Emily N W, Stoye David Q, Cox Simon R, Wardlaw Joanna M, Drake Amanda J, Bastin Mark E, Boardman James P

Abstract excerpt

MRI has enhanced our capacity to understand variations in brain structure and function conferred by the genome. We identified 60 studies that report associations between DNA methylation (DNAm) and human brain structure/function. Forty-three studies measured candidate loci DNAm; seventeen measured epigenome-wide DNAm. MRI features included region-of-interest and whole-brain structural, diffusion and functional...

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Identifiers

PMID: 32151655
DOI: 10.1016/j.neubiorev.2020.03.007
PMCID: PMC7237884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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