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Visual detection of DNA mutation using multicolor fluorescent coding.

ACS applied materials & interfaces - 27 Jun 2012

Song Jinzhao, Yang Qiong, Lv Fengting, Liu Libing, Wang Shu

Abstract excerpt

A visual colorimetric method for detecting multiplex DNA mutations has been developed using multicolor fluorescent coding based on multistep FRET of cationic conjugated polymers. Expensive instruments and technical expertise are not required in this method. Also our visual system provides a quantitative detection by simply analyzing RGB values of images. Genomic DNAs extracted from 60 FFPE colon tissues can be...

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PMID: 22698148
DOI: 10.1021/am300830r

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