Article
Leptin and mucosal immunity.
Mucosal immunology - 1 Sept 2012
Mackey-Lawrence N M, Petri W A
Abstract excerpt
Enhanced susceptibility to infection has long been recognized in children with congenital deficiency of leptin or its receptor. Studies in mice have demonstrated that leptin deficiency affects both the innate and acquired immune systems. Here, we review recent studies that demonstrate the impact on immunity of a common non-synonomous polymorphism of the leptin receptor. In a Bangladesh cohort of children, the...
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