Article
Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells.
Biomedical materials (Bristol, England) - 1 Aug 2012
Colley Helen, McArthur Sally L, Stolzing Alexandra, Scutt Andy
Abstract excerpt
Mesenchymal stem cells (MSC) are multipotent cells capable of differentiating into a number of mesenchymal tissues including bone, cartilage, and tendon. Low numbers in vivo means exponential growth is needed in culture to enable therapeutic applications. MSC can expand rapidly in culture but usually lose their extensive capacity for differentiation that makes them therapeutically attractive. To try and maintain...
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