Article
No increased trapping of multipotent mesenchymal stromal cells in bone marrow filters compared with other bone marrow cells.
Cytotherapy - 1 Jan 2008
Sundin M, Remberger M, Lönnies H, Sundberg B, Ringdén O, Le Blanc K
Abstract excerpt
BACKGROUND: Multipotent mesenchymal stromal cells (MSC) are candidates for cellular therapy in regenerative medicine and as treatment of graft-versus-host-disease (GvHD) after hematopoietic stem cell (HSC) transplantation. It has been suggested that MSC may be trapped in bone marrow (BM) filters during the stem cell procurement and lost from the HSC graft. METHODS: We investigated filtered BM and filters from six...
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