Article
Fibrin-based 3D matrices induce angiogenic behavior of adipose-derived stem cells.
Acta biomaterialia - 1 Apr 2015
Chung Eunna, Rytlewski Julie A, Merchant Arjun G, Dhada Kabir S, Lewis Evan W, Suggs Laura J
Abstract excerpt
Engineered three-dimensional biomaterials are known to affect the regenerative capacity of stem cells. The extent to which these materials can modify cellular activities is still poorly understood, particularly for adipose-derived stem cells (ASCs). This study evaluates PEGylated fibrin (P-fibrin) gels as an ASC-carrying scaffold for encouraging local angiogenesis by comparing with two commonly used hydrogels...
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