Article
Differential effect of platelet-rich plasma and fetal calf serum on bone marrow-derived human mesenchymal stromal cells expanded in vitro.
Journal of tissue engineering and regenerative medicine - 1 Aug 2011
Goedecke Anja, Wobus Manja, Krech Mathias, Münch Nadine, Richter Katja, Hölig Kristina, Bornhauser Martin
Abstract excerpt
Mesenchymal stromal cells (MSCs) derived from various sources have great potential for use in cell-based therapies. Since the proportion of primary MSCs contained in bone marrow or adipose tissue is low, plastic adherence and in vitro expansion are necessary to expand MSCs prior to clinical application. Human platelet-rich plasma has been introduced as an alternative serum source but functional differences have...
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