Article
Effects of a mixture of growth factors and proteins on the development of the osteogenic phenotype in human alveolar bone cell cultures.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Jul 2008
de Oliveira Paulo Tambasco, de Oliva Marcos Andrade, Maximiano William Marcatti Amarú, Sebastião Karen Elaine Vasconcelos, Crippa Grasiele Edilaine, Ciancaglini Pietro, Beloti Márcio Mateus, Nanci Antonio, Rosa Adalberto Luiz
Abstract excerpt
Strategies to promote bone repair have included exposure of cells to growth factor (GF) preparations from blood that generally include proteins as part of a complex mixture. This study aimed to evaluate the effects of such a mixture on different parameters of the development of the osteogenic phenotype in vitro. Osteoblastic cells were obtained by enzymatic digestion of human alveolar bone and cultured under...
Topics
- Alkaline Phosphatase
- Animals
- Becaplermin
- Blood Platelets
- Blood Proteins
- Cell Survival
- Cells, Cultured
- Core Binding Factor Alpha 1 Subunit
- Culture Media