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Article

A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells.

Stem cell research - 1 Mar 2016

González Sheyla, Mei Hua, Nakatsu Martin N, Baclagon Elfren R, Deng Sophie X

Abstract excerpt

The standard method of cultivating limbal epithelial progenitor/stem cells (LSCs) on a monolayer of mouse 3T3 feeder cells possesses the risk of cross-contamination in clinical applications. Human feeder cells have been used to eliminate this risk; however, efficiency from xenobiotic-free cultures on a monolayer appears to be lower than in the standard method using 3T3 cells. We investigated whether bone marrow...

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Identifiers

PMID: 26896856
DOI: 10.1016/j.scr.2016.02.018
PMCID: PMC4828302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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