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Article

Circulating immune cell phenotypes are associated with inflammatory biomarkers in dementia-free participants from the Framingham Heart Study Offspring cohort.

Scientific reports - 27 Feb 2026

Chen Jiachen, Doyle Margaret F, Cao Yumeng, Iyer Sandhya, Ragab Ahmed A Y, Murabito Joanne M, Lunetta Kathryn L

Abstract excerpt

Inflammatory responses are characterized by the activation of immune cells, while inflammatory biomarkers intricately interact with the immune system. While experimental studies have provided important mechanistic insights, large community-based investigations jointly profiling immune cell phenotypes and inflammatory biomarkers remain limited. This study aims to investigate the association between circulating...

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Identifiers

PMID: 41760714
DOI: 10.1038/s41598-026-41423-4
PMCID: PMC13049175

Genes

CD8A
CD27
CD4
CD40
CD5
CXCL10
CXCL9
TNF
TNFRSF9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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