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Article

Association of interleukin-(IL)10 haplotypes and serum IL-10 levels in the progression of childhood immune thrombocytopenic purpura.

Gene - 15 Aug 2012

Tesse Riccardina, Del Vecchio Giovanni Carlo, De Mattia Domenico, Sangerardi Maria, Valente Federica, Giordano Paola

Abstract excerpt

Derangement of genetic and immunological factors seems to have a pivotal role in the pathophysiology of immune thrombocytopenic purpura (ITP). We investigated interleukin(IL)-10 genetically determined expression in children with an acute progression of ITP (n=41) compared to young patients with chronic ITP (n=44) and healthy controls (n=60), and attempted to correlate IL-10 production with the course of the...

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Identifiers

PMID: 22677268
DOI: 10.1016/j.gene.2012.05.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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