Article
Cytokine gene polymorphism [tumor necrosis factor-alpha (-308), IL-10 (-1082), IL-6 (-174), IL-17F, 1RaVNTR] in pediatric patients with primary immune thrombocytopenia and response to different treatment modalities.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2016
Mokhtar Galila M, El-Beblawy Nagham M S, Adly Amira A, Elbarbary Nancy S, Kamal Tarek M, Hasan Esraa M
Abstract excerpt
To evaluate the association between development, progression, and response to therapy among patients with immune thrombocytopenia (ITP) and different cytokine gene polymorphisms known to be related to autoimmunity [tumor necrosis factor (TNF)-alpha, interleukin (IL)-10, IL-6, IL-17, IL-1Ra]. A total of 50 pediatric patients with ITP (20 newly diagnosed, 30 chronic) and 50 healthy controls were investigated via...
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