Article
Investigation of TNF-alpha, TGF-beta 1, IL-10, IL-6, IFN-gamma, MBL, GPIA, and IL1A gene polymorphisms in patients with idiopathic thrombocytopenic purpura.
Platelets - 1 Jan 2011
Pehlivan M, Okan V, Sever T, Balci S Oguzkan, Yilmaz M, Babacan T, Pehlıvan S
Abstract excerpt
Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterized by the presence of autoantibodies developing against thrombocyte membrane glycoproteins (GPs), such as GPIIa/IIIa and GPIb/IX. Single nucleotide polymorphisms (SNPs) of inflammatory cytokine genes were investigated in 71 patients with chronic ITP and 71 healthy controls, and they were compared with the clinical parameters. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
