Article
Role of transforming growth factor-beta 1 gene polymorphisms in childhood idiopathic thrombocytopenic purpura.
Journal of pediatric hematology/oncology - 1 Nov 2003
Atabay Berna, Oren Hale, Irken Gülersu, Kizildağ Sefa, Tunali Sunay, Türker Meral, Yilmaz Sebnem
Abstract excerpt
PURPOSE: To investigate whether transforming growth factor-beta 1 (TGF-beta 1) gene polymorphisms have a role in the development, clinical progress, and treatment response in children with idiopathic thrombocytopenic purpura (ITP). PATIENTS AND METHODS: Thirty-five children with acute ITP, 40 children with chronic ITP, and 97 healthy children were enrolled. After genomic DNA was extracted, TGF-beta 1 gene 509...
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