Article
TGFβ and IL10 have an impact on risk group and prognosis in childhood ALL.
Pediatric blood & cancer - 1 Jan 2015
Winkler B, Taschik J, Haubitz I, Eyrich M, Schlegel P G, Wiegering V
Abstract excerpt
BACKGROUND: Cytokines and their genes have been described to have an influence on incidence and prognosis in malignant, infectious and autoimmune disease. We previously described the impact of cytokine production on prognosis in paediatric standard-risk acute lymphoblastic leukaemia (ALL). PROCEDURE: In this study, we investigated the influence of cytokine gene polymorphisms (TNFα, TGFβ, IL10 and IFNγ) on...
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