Article
MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007
Urayama Kevin Y, Wiencke John K, Buffler Patricia A, Chokkalingam Anand P, Metayer Catherine, Wiemels Joseph L
Abstract excerpt
OBJECTIVE: The multidrug resistance (MDR) 1 gene encodes a membrane transporter called P-glycoprotein, which plays an important role in protecting cells against lipophilic xenobiotics by way of an ATP-dependent cellular efflux mechanism. Among children enrolled in the Northern California Childhoo...
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