Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007

Urayama Kevin Y, Wiencke John K, Buffler Patricia A, Chokkalingam Anand P, Metayer Catherine, Wiemels Joseph L

Abstract excerpt

OBJECTIVE: The multidrug resistance (MDR) 1 gene encodes a membrane transporter called P-glycoprotein, which plays an important role in protecting cells against lipophilic xenobiotics by way of an ATP-dependent cellular efflux mechanism. Among children enrolled in the Northern California Childhood Leukemia Study, we examined the susceptibility conferred by MDR1 single nucleotide polymorphisms (SNP) and predicted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Infant
Share to Air Pollution, Indoor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Child, Preschool

Share to Genes, MDR

Share to Haplotypes

Share to Insecticides

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 17548681
DOI: 10.1158/1055-9965.EPI-07-0007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia.PMID 17548681Read ↗

Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Risk of childhood leukemia associated with exposure to pesticides and with gene polymorphisms.Semantic proximity Read ↗

Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes.Semantic proximity Read ↗

Do polymorphisms in ABC transporter genes influence risk of childhood acute lymphoblastic leukemia?Semantic proximity Read ↗

Risk of brain tumors in children and susceptibility to organophosphorus insecticides: the potential role of paraoxonase (PON1).Semantic proximity Read ↗

Polymorphisms in CYP1A1 and ethnic-specific susceptibility to acute lymphoblastic leukemia in children.Semantic proximity Read ↗

Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities.Semantic proximity Read ↗

Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

ARID5B, IKZF1 and non-genetic factors in the etiology of childhood acute lymphoblastic leukemia: the ESCALE study.Semantic proximity Read ↗

Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood LeukemiaSemantic proximity Read ↗

Critical confluence: gene variants, insecticide exposure may increase childhood brain tumor risk.Semantic proximity Read ↗

Maternal Exposure to Pesticides, Paternal Occupation in the Army/Police Force, and CYP2D6*4 Polymorphism in the Etiology of Childhood Acute Leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.