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Article

Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes.

Environmental health perspectives - 1 Jan 2010

Searles Nielsen Susan, McKean-Cowdin Roberta, Farin Federico M, Holly Elizabeth A, Preston-Martin Susan, Mueller Beth A

Abstract excerpt

BACKGROUND: Insecticides that target the nervous system may play a role in the development of childhood brain tumors (CBTs). Constitutive genetic variation affects metabolism of these chemicals. METHODS: We analyzed population-based case-control data to examine whether CBT is associated with the functional genetic polymorphisms PON1C-108T, PON1Q192R, PON1L55M, BCHEA539T, FMO1C-9536A, FMO3E158K, ALDH3A1S134A, and...

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Source

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Identifiers

PMID: 20056567
DOI: 10.1289/ehp.0901226
PMCID: PMC2831959

Genes

FMO1
PON1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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