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Article

Expression of proto-oncogene KIT is up-regulated in subset of human meningiomas.

BMC cancer - 6 Jun 2012

Saini Masum, Jha Ajaya Nand, Abrari Andleeb, Ali Sher

Abstract excerpt

BACKGROUND: KIT is a proto-oncogene involved in diverse neoplastic processes. Aberrant kinase activity of the KIT receptor has been targeted by tyrosine kinase inhibitor (TKI) therapy in different neoplasias. In all the earlier studies, KIT expression was reported to be absent in meningiomas. However, we observed KIT mRNA expression in some meningioma cases. This prompted us to undertake its detailed analyses in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22672386
DOI: 10.1186/1471-2407-12-212
PMCID: PMC3443037

Genes

KIT
KITLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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