Clinical and molecular evidence for c-kit receptor as a therapeutic target in neuroblastic tumors.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinical and molecular evidence for c-kit receptor as a therapeutic target in neuroblastic tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2005

Uccini Stefania, Mannarino Olga, McDowell Heather P, Pauser Ursula, Vitali Roberta, Natali Pier Giorgio, Altavista Pierluigi, Andreano Tiziana, Coco Simona, Boldrini Renata, Bosco Sandro, Clerico Anna, Cozzi Denis, Donfrancesco Alberto, Inserra Alessandro, Kokai George, Losty Paul D, Nicotra Maria R, Raschellà Giuseppe, Tonini Gian Paolo, Dominici Carlo

Abstract excerpt

PURPOSE: Clinicobiological characteristics of neuroblastic tumor (NT) expressing c-kit tyrosine kinase receptor and/or its ligand, stem cell factor (SCF), are debated. This study aimed at investigating the clinicobiological features of primary NTs expressing c-kit and/or SCF in order to define the clinical relevance of selective therapeutic targeting. EXPERIMENTAL DESIGN: c-Kit and SCF expression was studied in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to Blotting, Southern

Share to Multivariate Analysis

Share to Neuroblastoma

Share to Proportional Hazards Models

Share to Proto-Oncogene Proteins c-kit

Share to Stem Cell Factor

Source

Open in PubMed

Identifiers

PMID: 15671569

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and molecular evidence for c-kit receptor as a therapeutic target in neuroblastic tumors.PMID 15671569Read ↗

No GIST-type c-kit gain of function mutations in neuroblastic tumours.Semantic proximity Read ↗

Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells.Semantic proximity Read ↗

c-Kit Receptors as a Therapeutic Target in Cancer: Current InsightsSemantic proximity Read ↗

C-KIT signaling in cancer treatment.Semantic proximity Read ↗

The C-Kit Receptor-Mediated Signal Transduction and Tumor-Related DiseasesSemantic proximity Read ↗

KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation.Semantic proximity Read ↗

Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical ImplicationsSemantic proximity Read ↗

Targeting c-Kit mutations: basic science to novel therapies.Semantic proximity Read ↗

c-Kit—A hematopoietic cell essential receptor tyrosine kinaseSemantic proximity Read ↗

Receptor tyrosine kinases in sinonasal undifferentiated carcinomas--evaluation for EGFR, c-KIT, and HER2/neu expression.Semantic proximity Read ↗

Molecular Alterations of <i>KIT</i> Oncogene in GliomasSemantic proximity Read ↗

A human embryonic stem cell–based model reveals the cell of origin of FOXR2-activated CNS neuroblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.