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Article

Molecular Alterations of <i>KIT</i> Oncogene in Gliomas

1 Jan 2007

Abstract excerpt

Gliomas are the most common and devastating primary brain tumours. Despite therapeutic advances, the majority of gliomas do not respond either to chemo or radiotherapy. KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. Currently, KIT constitutes an attractive therapeutic target. In the present study we assessed the frequency of KIT overexpression in gliomas and...

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Identifiers

PMID: 17726262
DOI: 10.1155/2007/926274

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