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Article

KIT gene mutation and amplification in dysgerminoma of the ovary.

Cancer - 15 May 2011

Cheng Liang, Roth Lawrence M, Zhang Shaobo, Wang Mingsheng, Morton Michael J, Zheng Wenxin, Abdul Karim Fadi W, Montironi Rodolfo, Lopez-Beltran Antonio

Abstract excerpt

BACKGROUND: Dysgerminoma, the ovarian counterpart of seminoma, is the most common type of malignant ovarian germ cell tumor. The role of KIT mutation and amplification in the development of dysgerminoma is not currently established. The purpose of this study was to analyze alterations of the KIT gene in a large series of dysgerminomas and correlate the findings with clinicopathological parameters. METHODS:...

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Source

Identifiers

PMID: 21523721
DOI: 10.1002/cncr.25794

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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