Article
Cell cycle control of p53 in normal (3T3) and chemically transformed (Meth A) mouse cells. II. Requirement for cell cycle progression.
Oncogene - 1 Nov 1990
Deppert W, Buschhausen-Denker G, Patschinsky T, Steinmeyer K
Abstract excerpt
To further characterize the role of p53 in growing normal Balb/c 3T3 fibroblasts, as well as of p53 in cells of the methylcholanthrene induced fibrosarcoma cell line Meth A, we analysed the effect of inhibition of p53 synthesis by microinjection of p53-specific monoclonal antibody PAb 122 into th...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Cycle
- Cell Division
- Cell Line
- Cell Line, Transformed
- Cell Nucleus
- Fibroblasts
- Fibrosarcoma
- G1 Phase
- Gene Expression
- Isoleucine
- Kinetics
- Methylcholanthrene
- Mice
- Mice, Inbred BALB C
- Microinjections
- Mutation