Article
Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Feb 1998
Glaise D, Ilyin G P, Loyer P, Cariou S, Bilodeau M, Lucas J, Puisieux A, Ozturk M, Guguen-Guillouzo C
Abstract excerpt
Several novel differentiated cell lines have been derived from a human hepatocarcinoma named HBG. Analysis of their functional properties evidenced a gradual differentiation process as they became confluent and a remarkable stability of the whole quiescent population for at least 6 weeks. However...
Topics
- Animals
- Apoptosis
- CDC2 Protein Kinase
- Carcinoma, Hepatocellular
- Cell Cycle
- Cell Differentiation
- Cell Division
- Cyclin-Dependent Kinases
- Cyclins
- Enzyme Inhibitors
- G1 Phase
- Gene Expression Regulation
- Genes, Retinoblastoma
- Genes, cdc
- Genes, myc
- Genes, p53
- Humans
- Liver