Article
Expression of Regulatory T–Cell-Related Molecule Genes and Clinical Outcome in Kidney Transplant Recipients
27 Mar 2009
Abstract excerpt
BACKGROUND: Naturally occurring regulatory T cells have been associated with long-term allograft survival. We investigated whether gene transcripts of Treg-related molecules are upregulated or downregulated in kidney transplant recipients with different clinical outcomes and may serve as markers of operative tolerance. METHODS: Expression levels of transcription factor (forkhead box P3 [FOXP3], t-bet, and GATA3),...
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