Article
Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy.
PloS one - 1 Jan 2014
Kamburova Elena G, Koenen Hans J P M, van den Hoogen Martijn W F, Baas Marije C, Joosten Irma, Hilbrands Luuk B
Abstract excerpt
BACKGROUND: Prevention of rejection after renal transplantation requires treatment with immunosuppressive drugs. Data on their in vivo effects on T- and B-cell phenotype and function are limited. METHODS: In a randomized double-blind placebo-controlled study to prevent renal allograft rejection, patients were treated with tacrolimus, mycophenolate mofetil (MMF), steroids, and a single dose of rituximab or placebo...
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