Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease.

PloS one - 1 Jan 2012

Agúndez José A, García-Martin Elena, Maestro María L, Cuenca Francisca, Martínez Carmen, Ortega Luis, Carballo Miguel, Vidaurreta Marta, Agreda Marta, Díaz-Zelaya Gabriela, Suárez Avelina, Díaz-Rubio Manuel, Ladero José M

Abstract excerpt

BACKGROUND/AIMS: Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the clinical course from mild chronic hepatitis C to hepatocellular carcinoma. METHODS: We have determined the rs12979860 single nucleotide polymorphism (SNP) upstream...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Hepacivirus
Share to Hepatitis C, Chronic
Share to Interferons
Share to Interleukins
Share to Liver Diseases
Share to Liver Neoplasms
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 22666430
DOI: 10.1371/journal.pone.0037998
PMCID: PMC3362530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease.PMID 22666430Read ↗

Impact of IL28B genetic variation on HCV-induced liver fibrosis, inflammation, and steatosis: a meta-analysis.Semantic proximity Read ↗

IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4.Semantic proximity Read ↗

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.Semantic proximity Read ↗

IL28B polymorphism as a predictor of antiviral response in chronic hepatitis C.Semantic proximity Read ↗

The association of IL28B genotype with the histological features of chronic hepatitis C is HCV genotype dependent.Semantic proximity Read ↗

IL28B rs12979860 gene polymorphism in Egyptian patients with chronic liver disease infected with HCV.Semantic proximity Read ↗

Correlation between genetic variations and serum level of interleukin 28B with virus genotypes and disease progression in chronic hepatitis C virus infection.Semantic proximity Read ↗

Impact of immunogenetic IL28B polymorphism on natural outcome of HCV infection.Semantic proximity Read ↗

Role of interleukin 28B rs12979860 C/T polymorphism on the histological outcome of chronic hepatitis C: relationship with gender and viral genotype.Semantic proximity Read ↗

Chronic hepatitis B and IL28B rs12979860 polymorphism: preliminary study.Semantic proximity Read ↗

Interleukin-28B TT genotype is frequently found in patients with hepatitis C virus cirrhosis but does not influence hepatocarcinogenesis.Semantic proximity Read ↗

Genetics of IL28B and HCV--response to infection and treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.