Article
The association of IL28B genotype with the histological features of chronic hepatitis C is HCV genotype dependent.
International journal of molecular sciences - 25 Apr 2014
D'Ambrosio Roberta, Aghemo Alessio, De Francesco Raffaele, Rumi Maria Grazia, Galmozzi Enrico, De Nicola Stella, Cheroni Cristina, Clark Paul J, Ronchi Guido, Lampertico Pietro, Colombo Massimo
Abstract excerpt
The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatitis C virus (HCV) genotype 1 and 4 patients. Its association with the histological features of chronic hepatitis C and disease severity needs further clarifications. To assess the correlation between IL28B genotype, HCV genotype and liver biopsy findings in untreated patients. MATERIALS AND METHODS: Pre-treatment...
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